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More importantly, many preclinical studies have shown that when anti-tumor drugs are combined with FAO inhibitors, cancer cell resistance to drugs can be reversed and the effectiveness of tumor therapy is enhanced

Reported tolerance is generally good, but generally well tolerated doesnt mean zero risk for everyone

(2018) Repurposing auranofin, ebselen, and PX-12 as antimicrobial agents targeting the thioredoxin system

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Hale AT, Tian H, Anih E, Recio FO, Shatat MA, Johnson T, et al

Although genetic diagnoses in CAS to date have largely been de novo high impact variants in neurodevelopmental genes, the genetic architecture of CAS is likely to also encompass polygenic inheritance of common variants and rare inherited variants with incomplete penetrance and variable expressivity