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In terms of hospital admissions, you may end up spending between $50,000 and $200,000 per year due to lung cancer, cardiovascular disease, respiratory diseases or oesophageal cancer, to name just a few smoking-attributable diseases

[51] A 2014 in vitro study demonstrated that e-cigarette use of a "balsamic" flavor with no nicotine can activate the release of proinflammatory cytokine in lung epithelial cells and keratinocytes

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Kenneth Michael Cummings, PhD, who co-leads the tobacco control research program at the Medical University of South Carolina, suspects the difference may be due to selection bias