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GSH is a crucial antioxidant

Ni NPs can significantly reduce the body weight, serum testosterone levels, and daily sperm production in Sprague Dawley rats, while the testicular index, nickel accumulation, and histological changes in testicular tissue increase with the dose of Ni NPs [74]

2) and (2) the seven reported suppressor mutations from the yeast model of disease can be all mapped onto the hydrophobic face of the regulatory domain that forms the BatemanBateman interface (Fig