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Arg1809: genotype-phenotype correlation

Water Retention : May cause mild swelling

While MELAS is traditionally considered a neurodegenerative disorder, symptoms such as delayed development and growth in early-onset patients or psychiatric conditions in some adult-onset MELAS patients suggest underlying neurodevelopmental deficits

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doi: 10.4293/JSLS.2024.00058 Bharti Sharma , Munirah Hasan , Usha S Govindarajulu , George Agriantonis , Navin D Bhatia , Jasmine Dave , Juan Mestre , Shalini Arora , Saad Bhatti , Zahra Shafaee , Suganda Phalakornkul , Kate Twelker , Jennifer Whittington