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In Embodiment 3 of this disclosure are compounds of Formula I, or any one of Embodiments 1-2, or a pharmaceutically acceptable salt of any of the foregoing, wherein R 1 is In Embodiment 4 of this disclosure are compounds of Formula I, or any one of Embodiments 1-3 or a pharmaceutically acceptable salt of any of the foregoing, wherein R 1 is phenyl substituted with a substituent selected from: hydroxy, halogen CN, C 1-3 alkyl, C 1-3 alkyl-CN, OC 1-3 alkyl-CN, C 1-3 haloalkyl, C 3-6 cycloalkyl, OC 1-3 alkyl, OC 1-3 haloalkyl, O-cyclopropyl, 5 membered heteroaryl containing 2 nitrogen atoms, S(O) 2 C 1-3 alkyl, S(O) 2 NHC 1-3 alkyl, or C 1-3 alkylNH 2 , and wherein the cycloalkyl moiety is optionally further substituted with F, CH 3 , CF 3 , CN, or OH

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The glycan sugar component (galactose, fucose, and mannose) of sIgA contributes to sIgA resistance to proteolysis in the intestine and functions through a broad spectrum of binding of pathogenic bacteria when compared with the antigen specific binding of the variable region of the Ig structure

Vitamin B12 also assists with the production of red blood cells and can help prevent anemia, which occurs when the blood does not have enough healthy red blood cells to transport sufficient oxygen throughout the body

NAC-SNPs/pALG co-treatment effectively mitigated these effects by improving growth indices, enhancing antioxidant enzyme activities, suppressing cortisol and inflammatory markers, and upregulating the Nrf2/HO-1 pathway