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As expected, patients with high SAAM scores exhibited low TMB, while those with low SAAM scores showed high TMB (Figure S6B)

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Some of the non-genetic regulatory mechanisms reported to underlie the formation of DTP cells 1,5761 are described subsequently, but this remains an evolving field and overall much remains to be understood

Most researchers have been focusing on the development of efficient and rapidly responsive thermosensitive biomaterials such as Pluronic F127 in a non-covalent manner, sodium chitosan/-glycerophosphate, and furan dimer gelatin covalently cross-linked by click chemistry with maleimide-functionalized polyethylene glycol (PEG) [204]