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FIGURE 6 A correlation analysis was conducted to investigate the relationships between gut microbiota and indicators of inflammatory injury and oxidative stress induced by DSS

[1] [13] This condition affects approximately one in three adults in the UK and exists in two main forms: non-alcoholic fatty liver disease (NAFLD) , which develops in people who drink little or no alcohol, and alcohol-related liver disease (ARLD) , caused by excessive alcohol consumption

Conversely, after APAP injection in hepatic specific PGC-1 overexpressing mice, the high expression of primary ROS scavengers is not able to counteract the hepatic oxidative stress induced by APAP, due to the collapse of GSH reservoir caused by the lowered Gcl-c expression and by the massive utilization of GSH for NAPQI detoxification performed by Glutathione S-Transferases

For the FASTA-based searches, DIA-NN was configured to conduct in-silico digestion of the protein sequences

doi: 10.1016/j.bbi.2010.04.012 230 KuratsuneH