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Description

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Ellingson, B

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5b) targeting the tumor protein CREPT by fusing a cationic pentapeptide membrane translocation sequence (KRRRRR) to the C-terminus, which enhanced transmembrane delivery and enabled effective degradation of endogenous CREPT in pancreatic cancer cells [225]

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One practical consideration: higher-concentration solutions (2000mcg/mL or above) increase the risk of peptide aggregation during long-term storage, so unless your protocol specifically requires minimal injection volumes, a 1000mcg/mL concentration is the safer choice for multi-week studies

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How This Treatment Works: The Science Behind the Combination 1

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