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Results: Among 33 participants (median 12.5 years experience), COSMOS had substantial inter-rater reliability (Congers Kappa 0.77, 95%CI:0.72-0.84) and almost-perfect intra-rater availability (Kappa 0.85, 0.82-0.88)

J Hepatol 55:683691 Hoofnagle JH (2013) LiverTox: a website on drug-induced liver injury

3.5 Antitumor effects Polysaccharides from Scrophularia ningpoensis significantly increase the thymus and spleen indices and prolonge survival in S180 tumor-bearing mice (95)

Attracted B cells are present in approximately 60% of SG in pSS patients (105)

Feng J, Lu P-z, Zhu G-z, et al: ACSL4 is a predictive biomarker of sorafenib sensitivity in hepatocellular carcinoma

* **Reparacin de tejidos:** Se cree que el cobre promueve la sntesis de colgeno y elastina, protenas esenciales para la salud y la elasticidad de la piel