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Other complications of mitral valve disease may include: Irregular and often rapid heartbeat, called atrial fibrillation

Magnetic resonance spectroscopy (MRS) allows the insight into their pathophysiology through exploration of a range of biochemicals putatively relevant to aetiological processes, in particular mitochondrial dysfunction and energy metabolism

Furthermore, genetic deletion of Gpx1 markedly exacerbates atherosclerosis in Apoe -/- mice (398,399), while overexpression of Gpx4 in Apoe -/- mice inhibits atherogenesis (400)