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Thus, NPD4928 stabilizes endogenous FSP1 in a dose-dependent manner, indicating that NPD4928-dependent ferroptosis is primarily mediated through the inhibition of FSP1 activity

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Furthermore, MT acts as a signaling molecule that regulates plant resistance to viruses, thereby enhancing their overall defense capabilities

Insulin also significantly increased the MR effect on CHAC1 and SLC7A5 expression but had no effect on other ATF4-responsive genes shown to be sensitive to mTOR (e.g., PSAT1, ASNS, CARS, MARS, SESN2, EIF4EBP1, and DDIT4 (data not shown))