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Description

PGC-1alpha induces human RPE oxidative metabolism and antioxidant capacity

The enzyme glutamine-PRPP amidotransferase catalyzes this reaction

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J Clin Psychopharmacol 2013;33:719-20

In cancer cells, the use of glutamate-derived nitrogen for NEAA production may be favored in various types of cancer cells to preserve nitrogen for anabolic reactions 48 and may prevent apoptosis induced by ATF4 activation upon glutamine deprivation 6