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Retrieved August 26, 2020

Only under the assumption of the high IC 50 of 200 mM (61.85 mg/mL) the lack of CYP3A4 inhibition could be a problem of drug concentration, but this is probably not of clinical relevance, since 400 mg per day is already a relatively high dose

The absence of biliary glutathione does not appear to promote ultrastructural evidence of bile duct injury during reperfusion in the isolated perfused rat liver.