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Interestingly, much of the research has been based on doses far exceeding the recommended daily intake, both in individuals with pathological conditions and in healthy subjects

J Biomol NMR 25:153156 Radhakrishnan I, Prez-Alvarado GC, Parker D, Dyson HJ, Montminy MR, Wright PE (1997) Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator: coactivator interactions