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Stomach acid is crucial because it helps separate B12 from the protein its attached to in food

Glutathione (GSH) is an important antioxidant that scavenges ROS and free radicals, thereby preventing cellular peroxidation (Liu et al., 2022)

Autoimmunity 57(1):2317190 Luca AD, Severino A, Paolis PD, Cottone G, Luca LD, Falco MD, Porcellini A, Volpe M, Condorelli G (2003) P300/cAMP-response-element-binding-protein ('CREB)-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor

However, GPX4 is a selenoprotein with a unique structural conformation, and no clinically approved small molecule can yet fully restore its catalytic function in vivo (198)