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Factors favoring successful withdrawal of AEDs include a seizure-free period of 2 to 4 years, complete seizure control within 1 year of onset, an onset of seizures after age 2 but before age 35, and a normal neurologic examination and EEG

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25 The firm also has high hopes for mRNA technology beyond infectious diseases, including its investigational vaccines for melanoma and lung cancer

76 In recent years, the GATOR1 complex has been shown to play an important role in the pathogenesis of focal epilepsies, with DEPDC5 exhibiting a higher mutation frequency (approximately 85% of reported cases) than NPRL2 (5%) and NPRL3 (10%)

Inflammatory markers : TNF-, IL-6, IL-1 in serum/CSF

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