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Increasingly, however, SMOC1 has also been implicated in AD: a comprehensive analysis based on large-scale mass spectrometry, encompassing 14,513 brain proteins and 34,173 phosphorylation sites, revealed the temporal dynamics of 173 proteins across 17 critical pathways involved in AD progression [198]

The discovery and characterization of this molecule are quite recent and have been studied in detail by researchers at the University of Ghent (Belgium), in collaboration with Kings College London, who have succeeded in isolating the substance, defining it chemically (8-prenylna ringenin) and testing it with respect to functionality on human physiology